Figure 1. ; Schematic depictionof the two-step diagnostic scheme for the detection of MERS-CoV specific RNA by screening for two different sequence targets, e.g. upE and orf1a.

In case of inconsistent results of the screening assays, conformational sequencing or RT-PCR of a third target should be performed (modified from the diagnostic scheme recommended by WHO in 2012 [19]).

^†Positive only for one of the two targets.

^‡Where applicable: use of different/additional specimen type.