Table 2.
Results of univariate Cox proportional hazards regression between OS and 12 predictors. Four traditional prognostic measurements (serum CA19-9, global SUVmax, global SUVmean, and GTV) are categorized as baseline measurement (B), and post-RT versus pre-RT ratio (R). Surface measurements based on metabolic features only, anatomic features only and combined anatomic and metabolic features are indicated as Mdist|SUV, Mdist|Shape, Mdist|Fusion, respectively. Statistical significance are marked as * for p-values < 0.05, and ** for p-values < 0.01.
| Mean | Std | HR/exp() (95% CI) | p values | |
|---|---|---|---|---|
| Age | 68.20 | 9.52 | 1.14 (1.04–1.25) | 0.004** |
| CA19-9 (B) (k) | 2.62 | 11.8 | 0.99 (0.99–1.00) | >0.1 |
| CA19-9 (R) (n = 29) | 0.68 | 0.66 | 1.63 (0.70–3.77) | >0.1 |
| SUVmax (B) | 6.00 | 2.37 | 0.90 (0.72–1.13) | >0.1 |
| SUVmax (R) | 0.81 | 0.39 | 3.89 (0.94–16.02) | 0.060 |
| SUVmean (B) | 2.41 | 0.63 | 0.81 (0.32–2.04) | >0.1 |
| SUVmean (R) | 0.91 | 0.31 | 1.75 (0.45–6.75) | >0.1 |
| GTV (B) (cc) | 51.71 | 35.60 | 1.00 (1.00–1.00) | >0.1 |
| GTV (R) | 0.90 | 0.38 | 3.01 (0.57–15.71) | >0.1 |
| Mdist|SUV | 3.25 | 4.87 | 0.39 (0.24–1.13) | >0.1 |
| Mdist|Shape | 0.70 | 0.77 | 1.22 (0.69–2.14) | >0.1 |
| Mdist|Fusion | 2.68 | 4.62 | 0.52 (0.19–0.78) | 0.008** |