Table 5.
Multivariate analyses of predictive factors for the occurrence of infection (≥ grade 3) during the first 3 cycles of Len-dex treatment
| Multivariate variables | Model I | Model II | Model III | |||
|---|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P | Hazard ratio (95% CI) | P | Hazard ratio (95% CI) | P | |
| Frequency of CD3+CD4+CD161+ (%) | ||||||
| < 3.2 | 1 | |||||
| ≥ 3.2 | 0.18 (0.04–0.96) | 0.044 | – | – | – | – |
| Absolute count of CD3+CD4+CD161+ (cells/μL) | ||||||
| < 43 | – | – | 1 | – | – | |
| ≥ 43 | – | – | 0.13 (0.03–0.66) | 0.014 | – | – |
| Absolute count of CD3+ (cells/μL) | ||||||
| < 640 | – | – | – | – | 1 | |
| ≥ 640 | – | – | – | – | 0.66 (0.16–2.75) | 0.564 |
| Hb (g/dL), (≥ 10 vs. < 10) | 0.02 (0.00–0.17) | < 0.001 | 0.04 (0.01–0.26) | 0.001 | 0.05 (0.01–0.27) | 0.001 |
| Albumin (mg/dL), (≥ 3.5 vs. < 3.5) | 2.89 (0.43–19.34) | 0.247 | 3.97 (0.55–28.82) | 0.172 | 2.13 (0.37–12.33) | 0.399 |
| Creatinine (mg/dL), (≥ 2 vs. < 2) | 2.12 (0.31–14.62) | 0.446 | 1.78 (0.22–14.21) | 0.586 | 3.64 (0.62–21.17) | 0.151 |
CI confidence interval