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. 2020 Feb 4;94(5):e511–e520. doi: 10.1212/WNL.0000000000008747

Figure 3. Distribution of functional impairments during the disease course.

Figure 3

Distribution of (A) modified Rankin Scale (mRS) and (B) Karnofsky Performance Scale (KPS) scores at onset of symptoms; diagnosis; 1, 3, 6, 12, 24, 60, and 120 months after diagnosis; and maximal (max) disease severity. At diagnosis, 62% of patients were independent for self-care (KPS score ≥70), increasing to 68% 1 month later and 85% 1 year later. At maximum disease severity, 46% of patients were independent for self-care. Number of patients available at top of bar for each time point.