Table 1.

Statistically significant concentration levels of soluble factors in carvacrol treated samples compared to nontreated controls. All measurements were achieved by MAGPIX multiplexing assay. Red indicates a decrease whereas green illustrates an increase in concentrations compared to controls.

Groups	Soluble factors	Control (pg/mL)	Treated (pg/mL)	P- value	Evaluation
HT-29	GMCSF	104.0000	96.0000	0.028	decreased	FGF basic	55.4967	41.2467	0.028	decreased	GCSF	177.9967	116.7200	0.028	decreased	HGF	35.7567	27.9967	0.028	decreased	Leptin	17.7467	14.4967	0.028	decreased	Osteopontin	49.5000	61.6200	0.028	increased	PECAM1	72.7467	77.9967	0.028	increased	Prolactin	147.0000	53.4967	0.028	decreased	SCF	29.7467	46.2467	0.028	increased	sEGFR	57.9967	41.4967	0.028	decreased	sHER2neu	35.2467	22.9967	0.028	decreased	sIL6Ra	36.9967	12.4967	0.028	decreased	sTIE2	45.2467	44.0000	0.028	decreased	sVEGFR1	77.9967	10.4967	0.028	decreased	sVEGFR2	30.4967	14.9967	0.028	decreased	IL18	30.0000	19.4967	0.028	decreased	TGF	106.2467	25.9967	0.109	decreased	VEGFC	16.9967	40.9967	0.002	increased
	HCT-116	GMCSF	82.0000	105.0000	0.028	increased	IL8	30.0000	9.0000	0.028	decreased	FGF basic	22.4967	47.9967	0.028	increased	GCSF	116.2467	117.4967	0.028	increased	HGF	12.5000	15.0000	0.028	increased	Leptin	8.9967	23.4967	0.028	increased	Osteopontin	40.9933	53.5000	0.028	increased	PECAM1	16.4967	27.9967	0.028	increased	Prolactin	57.4967	117.0000	0.028	increased	SCF	44.7467	61.9967	0.028	increased	sHER2neu	28.2467	78.2467	0.028	increased	sIL6Ra	23.9967	27.4967	0.028	increased	sTIE2	39.2467	34.0000	0.028	decreased	sVEGFR1	72.2467	66.4967	0.028	decreased	sVEGFR2	10.0000	21.9967	0.028	increased	TGF	66.9967	23.9967	0.028	decreased