Figure 3.

NR administration reduces the angiotensin ‐–induced phenotypic transformation of smooth muscle cells. (A) Representative images of arterioles stained with H＆E in control, Ang ‐–treated, and NR‐treated mice after 28 d. (B‐C) Representative immunofluorescence images and the quantification analysis of α‐SMA in the 3 groups. (D‐E) Representative immunofluorescence images and the quantification analysis of PCNA in the 3 groups after staining with lectin. Scale bars: A = 100 μmol/L, B and D = 50 μm; *P < .05, **P < .01. Ang: angiotensin ‐, Ang + NR: angiotensin ‐+nicotinamide riboside. The results are presented as the means ± standard deviations (SDs)