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. 2020 Mar 18;2020(3):CD004953. doi: 10.1002/14651858.CD004953.pub4

NCT02858583.

Trial name or title SURV1VE‐Trial ‐ Sustained inflation and chest compression versus 3:1 chest compression to ventilation ratio during cardiopulmonary resuscitation of asphyxiated newborns: a randomised controlled trial
Methods Prospective randomised parallel controlled trial
Participants Infants (term or preterm infants) requiring chest compressions in the delivery room
Interventions SLI group: PIP of 25 to 30 cmH₂O for 45 seconds while receiving chest compression. This will be followed by PEEP of 5 to 8 cmH₂O. If heart rate < 60/min, continue with chest compression + SLI for another 45 seconds. If heart rate remains < 60/min, continue with CC + SI
Control group: chest compression at a rate of 90/min and 30 ventilations/min in a 3:1 C:V ratio
Outcomes Primary outcomes: return of spontaneous circulation; duration of chest compression heart rate is > 60/min for 15 seconds
Starting date January 2017
Contact information Georg Schmolzer, MD, PhD; georg.schmoelzer@me.com
University of Alberta
Notes Estimated enrolment: 218
Estimated primary completion date: May 2021