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. 2020 Mar 18;2020(3):CD004953. doi: 10.1002/14651858.CD004953.pub4

NCT02887924.

Trial name or title The effect of sustained lung inflation maneuver applied through nasal prong on early and late respiratory morbidities in preterm infants
Methods Prospective randomised parallel controlled trial
Participants Preterm infants of 26 weeks 0 days and 29 weeks 6 days
Interventions SLI group: PIP 25 cmH₂O for 15 seconds with T‐piece and bi‐nasal prongs; second SLI in case of poor response
Control group: CPAP
Outcomes Primary outcome: rate of surfactant, intubation and mechanical ventilation needs within first 72 hours of life
Secondary outcomes: heart rate, fractional inspiratory oxygen, CPAP pressure and oxygen saturation within first 72 hours of life in preterm infants; total non‐invasive, invasive respiratory support time; BPD; PDA; IVH, NEC; ROP; feeding intolerance, reaching birth weight; transition to full oral feeding time
Starting date August 2016
Contact information Zekai Tahir Burak Women's Health Research and Education Hospital, Ankara, Turkey
Notes Estimated enrolment: 250
Estimated primary completion date: September 2017