NCT02887924.
Trial name or title | The effect of sustained lung inflation maneuver applied through nasal prong on early and late respiratory morbidities in preterm infants |
Methods | Prospective randomised parallel controlled trial |
Participants | Preterm infants of 26 weeks 0 days and 29 weeks 6 days |
Interventions | SLI group: PIP 25 cmH₂O for 15 seconds with T‐piece and bi‐nasal prongs; second SLI in case of poor response Control group: CPAP |
Outcomes | Primary outcome: rate of surfactant, intubation and mechanical ventilation needs within first 72 hours of life Secondary outcomes: heart rate, fractional inspiratory oxygen, CPAP pressure and oxygen saturation within first 72 hours of life in preterm infants; total non‐invasive, invasive respiratory support time; BPD; PDA; IVH, NEC; ROP; feeding intolerance, reaching birth weight; transition to full oral feeding time |
Starting date | August 2016 |
Contact information | Zekai Tahir Burak Women's Health Research and Education Hospital, Ankara, Turkey |
Notes | Estimated enrolment: 250 Estimated primary completion date: September 2017 |