Table 6:
Atrial Fibrillation
| Author, Year N (TAVI/SAVR) | Atrial Fibrillation | ||
|---|---|---|---|
| 30 Days | 1 Year | 2 Years | |
| Full Cohort | |||
| Reardon et al, 201719 | Percentageb | Not reported | Not reported |
| SURTAVI, mITTa | TAVI: 12.9 | ||
| 1,660 (864/796) | SAVR: 43.4 | ||
| 95% Crl for difference: | |||
| −34.7 to −26.4 | |||
| Leon et al, 201610 | New AF, KM estimate n (%)d | New AF, KM estimate n (%)d | New AF, KM estimate n (%)d |
| PARTNER 2, ITTc | TAVI: 91 (9.1) | TAVI: 100 (10.1) | TAVI: 110 (11.3) |
| 2,032 (1,011/1,021) | SAVR: 265 (26.4) | SAVR: 272 (27.2) | SAVR: 273 (27.3) |
| P < .001 | P < .001 | P<.001 | |
| Transfemoral Cohort | |||
| Leon et al, 201610 | New AF, KM estimate n (%)d | New AF, KM estimate n (%)d | New AF, KM estimate n (%)d |
| PARTNER 2, ITTc | TAVI: 38 (4.9) | TAVI: 45 (5.9) | TAVI: 55 (7.4) |
| 1,550 (775/775) | SAVR: 204 (26.7) | SAVR: 210 (27.6) | SAVR: 211 (27.8) |
| P < .001 | P < .001 | P<.001 | |
| Transthoracic Cohort | |||
| Leon et al, 201610 | New AF, KM estimate n (%)d | New AF, KM estimate n (%)d | New AF, KM estimate n (%)d |
| PARTNER 2, ITTc | TAVI: 53 (22.8) | TAVI: 55 (23.8) | TAVI: 55 (23.8) |
| 482 (236/246) | SAVR: 61 (25.4) | SAVR: 62 (25.9) | SAVR: 62 (25.9) |
| P = .50 | P = .60 | P = .60 | |
Abbreviations: AF, atrial fibrillation; CrI, credible interval; KM, Kaplan–Meier; SAVR, surgical aortic valve replacement; TAVI, transcatheter aortic valve implantation.
a
mITT analysis refers to patients in whom the TAVI or SAVR procedure was at least attempted.
b
Calculated by means of Bayesian analyses.
c
ITT analysis includes all patients randomized to receive either TAVI or SAVR
d
The percentages provided are Kaplan–Meier estimates at the specific time point and do not necessarily equal the number of patients who experienced the event divided by the total number of patients in the treatment group at the given time point.