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. 2020 Mar 10;9(3):165–176. doi: 10.1002/psp4.12494

Figure 4.

Figure 4

Case study 1: Target‐mediated drug disposition model simulation results for alternative dosing regimens. The results show (a) free drug, (b) free target, and (c) total target concentrations of four different dosing regimens using the generated virtual population. In each plot, the solid line represents the weighted mean and the shaded region represents the 2.5th and 97.5th percentiles.