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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Biomed Pharmacother. 2020 Jan 29;125:109956. doi: 10.1016/j.biopha.2020.109956

Table 1.

PPM1D in cancers

Cancer type Amplification mRNA upregulation Protein upregulation Mutation Reference
Breast cancer + + + + 57,1011,13
Esophageal cancer + + + 21,22,23
Colon cancer + + + 24,26,27
Hematological tumor + + 35,37,39
Thyroid cancer + 41,42
sarcoma + + 44,45
Lung cancer + + + 48,49,53
Ovarian cancer + + + + 56,57,58,59,61
Pancreatic cancer + + 65
glioma + + + 67,69
Gastric cancer + 70,71
Nasopharyngeal carcinoma + + 72
Liver cancer + + 73,74,75
Renal carcinoma + + 76
Bladder cancer + + 77,
Prostate cancer + + 80,81
Oral cancer + 82
neuroblastoma + + 83,84
melanoma + + 85