Table 1.
Cancer type | Amplification | mRNA upregulation | Protein upregulation | Mutation | Reference |
---|---|---|---|---|---|
Breast cancer | + | + | + | + | 5–7,10–11,13 |
Esophageal cancer | − | + | + | + | 21,22,23 |
Colon cancer | − | + | + | + | 24,26,27 |
Hematological tumor | + | − | − | + | 35,37,39 |
Thyroid cancer | − | − | − | + | 41,42 |
sarcoma | − | + | + | − | 44,45 |
Lung cancer | − | + | + | + | 48,49,53 |
Ovarian cancer | + | + | + | + | 56,57,58,59,61 |
Pancreatic cancer | − | + | + | − | 65 |
glioma | + | + | − | + | 67,69 |
Gastric cancer | − | − | + | − | 70,71 |
Nasopharyngeal carcinoma | − | + | + | − | 72 |
Liver cancer | − | + | + | − | 73,74,75 |
Renal carcinoma | − | + | + | − | 76 |
Bladder cancer | − | + | + | − | 77, |
Prostate cancer | − | + | + | − | 80,81 |
Oral cancer | − | − | + | − | 82 |
neuroblastoma | − | + | + | − | 83,84 |
melanoma | − | + | + | − | 85 |