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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Hear Res. 2020 Feb 6;389:107905. doi: 10.1016/j.heares.2020.107905

Figure 3: Cisplatin-induced outer hair cell loss is reduced in cisplatin mice co-treated with lovastatin.

Figure 3:

Microdissected cochlear tissue immunofluorescently stained for myosin-VIIa were imaged for the purpose of quantifying inner and outer hair viability following cisplatin treatment. Representative images are shown from the cochlear apex (8 kHz), middle (22.4k Hz) and base (45 kHz) to show the HC densities for the three rows of OHC and single row of IHC for saline-treated control (1st row), cisplatin-treated (2nd row), cisplatin + low dose lovastatin (3rd row), and cisplatin + high dose lovastatin (4th row). See Figure 4 for quantification of each cell type.