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. Author manuscript; available in PMC: 2020 Mar 19.
Published in final edited form as: Neurorehabil Neural Repair. 2020 Jan 22;34(3):200–209. doi: 10.1177/1545968319895480

Figure 4. VNS-dependent recovery generalizes to similar, but untrained, forelimb tasks.

Figure 4.

(A) SCI reduces the total number of forepaw contacts on the cylinder task. VNS paired with rehabilitative training on the isometric pull task significantly increases spontaneous forelimb use during exploration compared to rehabilitative training without VNS, indicative of a generalization of forelimb recovery to a similar task. (B) Pairing VNS with training on the isometric pull task significantly increases grip strength compared to rehabilitative training without VNS. Unpaired t-tests across groups at each time point; ** denotes p < 0.01, *** p < 0.001. Error bars indicate mean ± SEM.