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Results from studies that evaluated outcomes according to direct oral anticoagulant dose adjustment. (A) Outcomes results for overall direct oral anticoagulants.11, 54 (B) Outcomes regarding dabigatran dose adjustments.11 (C) Outcomes evaluated according rivaroxaban dose adjustment.11 (D) Results from studies with outcomes regarding apixaban dose adjustments.11, 77 MI = myocardial infarction; SSE = stroke or systemic embolism
