Skip to main content
. 2020 Mar 12;11:124. doi: 10.3389/fendo.2020.00124

Figure 3.

Figure 3

Performance in the Fear Conditioning, Novel Object Recognition and Barnes Maze behavior tests. (A,B) Fear conditioning test performed with 15–19 weeks old WT, TauKO, and hTau mice (n = 7 WT; 6 TauKO; 7 hTau). Percentage of freezing behavior during the (A) contextual and (B) cued FC. (C) Novel object recognition test performed with 15–19 weeks old WT, TauKO, and hTau mice (n = 11 WT; 9 TauKO; 6 hTau). Exploration time of familiar and novel objects during the test phase. Time expressed in percentage. (D–G) Barnes maze test performed with 15–19 weeks old WT, TauKO, and hTau mice (n = 9 WT; 8 TauKO; 6 hTau). (D) Total number of errors and (E) Total latency to find the target zone in 4 different trials/day, for 4 days during the acquisition/training phase of the Barnes maze test. (F) Latency to find and (G) time in the target zone 24 h after the last training trial as a measure of spatial reference memory. Data are representative of at least two independent experiments. *p < 0.5.