Fig. 2.

Weight data of all male pups from the animal experiments are shown. Transcriptome analyses were performed in only 5 animals per group, remaining pups were used for other studies. a Birth weight (g) in C (n = 105), LP (n = 70), LIG (n = 52 small), and IUS (n = 99) pups. b Bodyweight (g) on postnatal day (PND) 7 in C, (n = 24), LP, (n = 16), LIG (n = 14), and IUS (n = 17) pups. c Absolute kidney weight and e kidney weight/body weight ratio of both kidneys of animals dissected on PND 1 in C (n = 27), LP (n = 17), LIG (n = 21), and IUS (n = 24) pups. d Absolute kidney weight and f kidney weight/body weight ratio of both kidneys of animals dissected on PND 7 (for numbers see legend to Fig. 2b). Significances are shown by asterisks for the comparisons LP–C, LIG–C, and IUS–C above the respective bar; *p < 0.05; **p < 0.01; ***p < 0.001 (all p values Bonferroni adjusted). Further comparisons with significant results: a LP–LIG, *; LIG–IUS, ***; b none; c LP–IUS, *; LIG–IUS, *; d LP–IUS, *; e LP–IUS, *; f none