Table 2.
Productivity of isoforms containing significant alternative 3’ events.
| Alternative 3′ splice-site coordinates | Is a multiple of 3 | Productive isoforms | Unproductive isoforms | Isoforms with no start/stop codon |
|---|---|---|---|---|
| chr2:241335958,241335974 | N | 1 | 1 | 0 |
| chr20:35556954,35556972 | Y | 1 | 0 | 0 |
| chr1:161710439,161710474 | N | 0 | 2 | 0 |
| chr5:133091165,133091192 | Y | 1 | 0 | 0 |
| chr6:15651408,15651363 | Y | 4 | 2 | 0 |
| chr17:81239567,81239594 | Y | 0 | 3 | 1 |
| chr1:1374590,1374445 | N | 0 | 1 | 0 |
| chr12:120498072,120498119 | N | 8 | 0 | 0 |
| chr3:186787478,186787494 | N | 0 | 8 | 0 |
| chr1:155310042,155310063 | Y | 3 | 5 | 0 |
| chr1:45013574,45013593 | N | 1 | 4 | 0 |
| chr2:202291020,202291124 | N | 0 | 8 | 0 |
The alternative 3′ splicing events displayed are those where the proximal splice site is preferred in SF3B1K700E samples. Only splicing events that affect coding regions are shown, and only isoforms using the proximal splice site were counted. Isoforms were counted if they have a minimum of 20 counts across SF3B1K700E samples.