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. 2020 Jan 6;35(3):687–695. doi: 10.1007/s11606-019-05445-1

Table 2.

Characteristics of Cases

No. of cases Sustained taper absolute dose reduction from peak dose, MME Sustained taper percent dose reduction from peak dose, % Sustained taper dose, MME
Median [IQR] Median [IQR] Median [IQR]
Total 894 60 [44–90] 69 [58–91] 24 [7–38]
Type of taper achieved
Discontinuation 200 75 [60–100] 100 [100–100] 0 [0–0]
Low ≤ 30 MME 410 47 [35–62] 69 [58–81] 23 [15–28]
Reduced ≥ 50% 284 75 [53–122] 58 [53–66] 50 [38.5–67.5]
Peak dose prior to taper
31–< 50 MME 21 25 [18–40] 51 [40–100] 21 [0–27]
50–< 90 MME 481 47 [37–59] 70 [57–93] 20 [5–28]
90–< 120 MME 165 72 [60–90] 71 [61–100] 27 [0–39]
120–< 150 MME 84 87 [75–114] 65 [58–92] 44 [10.5–56]
150–< 200 MME 66 122 [103–145] 68 [59–83] 54 [27–67]
200+ MME 77 192 [148–269] 68 [58–77] 90 [57–120]
Year of cohort entry
2011 531 66 [49–100] 68 [57–89] 27 [8–45]
2012 138 51 [39–80] 66 [57–85] 24.5 [11–31]
2013 81 53 [42–77] 73 [60–91] 20 [7–30]
2014 79 58 [43–75] 77 [61–100] 19 [0–28]
2015 65 55 [40–70] 74 [59–100] 19 [0–29]
Age group at cohort entry, years
18–40 87 61 [44–92] 77 [62–88] 20 [7–30]
41–60 507 62 [45–91] 68 [57–93] 26 [6–41]
61+ 300 58 [43–89] 68 [57–89] 24 [9–34]
Sex
Female 555 60 [44–90] 68 [58–89] 25 [8–37]
Male 339 61 [45–90] 71 [57–100] 24 [0–40]
Race
White 725 60 [44–90] 69 [58–91] 24 [7–38]
African-American 39 53 [43–90] 77 [56–100] 21 [0–30]
American Indian 19 61 [39–93] 69 [54–87] 23 [18–30]
Alaskan Native
Asian 4 62.5 [45–87.5] 63 [61–82] 26.5 [11.5–41.5]
Hawaiian or other 3 50 [34–74] 56 [52–62] 40 [32–46]
Pacific Islander
Other 16 55 [40–88.5] 61 [53–70] 30 [24.5–43]
Mixed (more than 1) 26 61 [45–68] 67 [55–84] 26 [9–41]
Hispanic origin
No 798 60 [44–90] 69 [57–90] 25 [8–37]
Yes 33 72 [45–89] 67 [59–100] 25 [0–40]