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. 2020 Mar 12;11:240. doi: 10.3389/fphar.2020.00240

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Copyright © 2020 Wang, Yang, Wu, Wang, Li, Mei, You and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DOP protected the intestinal mucosal barrier and maintained intestinal epithelial integrity in the CCl₄-induced liver fibrosis rat model. (A) The protein expression levels of Bcl-2, Bax and caspase-3 in the intestine. (B) The protein expression levels of ZO-1, occludin and claudin-1 in the intestine. (C) An immunohistochemical method was used to detect claudin-1. The images represented 2–3 different rats in each group (scar bar: 200 μm). Data are presented as the mean ± S.D. (n ≥ 3). ^#p < 0.05 and ^###p < 0.001 vs. NC. *p < 0.05, **p < 0.05, and ***p < 0.001 vs. FC. p = 0.10 vs. FC, and p = 0.056 vs. FC.