Table 4.

The correlation coefficient between superficial white matter AxD, MD, RD, FA, and MMSE scores

		NC		MCI		AD
		r	p	r	p	r	p
AxD	frontal	0.07	0.74	.130	0.51	–0.24	0.24
	insula	0.05	0.80	–0.14	0.51	–0.37	0.07
	limbic	–0.05	0.81	–0.004	0.98	–0.45	0.05
	occipital	0.09	0.67	–0.18	0.37	–0.39	0.05
	parietal	0.05	0.78	0.02	0.92	–0.42	0.04
	temporal	–0.1	0.61	0.21	0.30	–0.53	0.007
MD	frontal	0.12	0.55	0.19	0.36	–0.29	0.16
	insula	0.02	0.90	–0.25	0.23	–0.14	0.50
	limbic	0.12	0.56	–0.03	0.86	–0.39	0.05
	occipital	0.04	0.83	–0.12	0.54	–0.40	0.05
	parietal	0.11	0.59	–0.02	0.91	–0.49	0.01
	temporal	0.01	0.96	0.17	0.41	–0.49	0.01
RD	frontal	0.07	0.72	0.14	0.50	–0.30	0.14
	insula	–0.004	0.98	–0.22	0.28	–0.02	0.91
	limbic	0.06	0.76	–0.003	0.98	–0.37	0.07
	occipital	0.09	0.65	–0.07	0.74	–0.39	0.05
	parietal	0.11	0.60	–0.02	0.90	–0.51	0.01
	temporal	–0.08	0.69	0.17	0.41	–0.48	0.01
FA	frontal	–0.07	0.72	–0.28	0.17	0.12	0.57
	insula	–0.08	0.69	0.21	0.31	0.46	0.06
	limbic	–0.1	0.57	–0.1	0.63	0.19	0.35
	occipital	0.08	0.68	–0.11	0.58	0.29	0.16
	parietal	–0.2	0.32	0.002	0.99	0.37	0.07
	temporal	0.006	0.97	0.1	0.62	0.17	0.41

MMSE, Mini-Mental State Examination; AxD, axial diffusion; MD, mean diffusion; RD, radial diffusion; FA, fractional anisotropy; NC, normal controls; MCI, mild cognitive impairment; AD, Alzheimer’s disease. p < 0.05 was considered statistically significant and bold font indicates statistical significance.