1. Classification systems for describing mild cognitive impairment according to Matthews 2008.
System | Description | Impairment |
Age‐related cognitive change | ||
ACMI | Age‐consistent memory impairment |
Memories aging in accord with normative expectations; individual aged 50 to 79 and reports a decline in memory verified using objective memory testing performance (within ± 1 standard deviation of aged norms on 75% of tests (memory) administered); preserved general functioning. |
ARCD | Age‐related cognitive decline | Objectively identified decline in memory and cognitive functioning considered to be a normal consequence of aging. |
Category systems | ||
SMC | Subjective memory complaint | Self‐reported decline in memory. |
MMSE MCI | Mini‐Mental State Examination | Classification based on MMSE cut‐offs (maximum score 30). 'Normal' defined as a score from 27 to 30; MCI defined as a score from 22 to 26; and 'impaired' defined as a score < 21. |
Pathological decline | ||
MNCD | Mild neurocognitive disorder | Impairment resulting from a general medical condition; reported decline in cognitive functioning supported by formal testing; deficits observed in at least 2 areas of cognitive functioning; interference in social, occupational, or other areas of functioning. |
CIND | Cognitive impairment no dementia | Cognitive impairment in one or more domains (including memory and non‐memory domains) that can have a variety of aetiologies. |
BSF | Benign senescent Forgetfulness |
Impairment in remote memory and intact recent memory; awareness of the impairment and use of compensatory strategies. |
AAMI | Age‐associated memory impairment | Subjective and objective memory loss associated with normal aging; individual aged 50 and older and shows adequate intellectual function (i.e. without dementia). |
MD | Minimal dementia | Cognitive impairment in memory and minor and variable errors in orientation; no evidence of impaired occupational or social functioning; self care unimpaired. |
LCD | Limited cognitive disturbance | Reported decline in memory with use of compensatory strategies; occasional forgetfulness (e.g. names, places); 1 or 2 errors on cognitive (memory) testing. |
QD | Questionable dementia | Impaired memory and non‐memory test performance; no significant activity of daily living or instrumental activity of daily living interference. |
AACD | Age‐associated cognitive decline | Self‐ or informant report of cognitive decline (gradual and present for 6 months); objective difficulties in any of the following domains: learning and memory, attention and concentration, thinking, language, and visuospatial functioning |
MCD | Mild cognitive disorder | Decline in cognitive performance, including memory impairment and learning or concentration difficulties; complaint confirmed by cognitive tests; may precede, accompany, or follow a wide variety of infections or physical disorders. |
Mayo Clinic Criteria | ||
N‐MCI | Non‐amnestic mild cognitive impairment | Subjective memory complaint; normal general cognitive function; normal range of activities of daily living; objective impairment in 1 or more domains other than memory. |
A‐MCI | Amnestic mild cognitive impairment | Subjective memory complaint; normal general cognitive function; normal range of activities of daily living; impaired memory performance; normal non‐memory test performance |
M‐MCI | Multiple mild cognitive impairment | Subjective memory complaint; normal general cognitive function; normal range of activities of daily living; impaired memory and nonmemory test performance |