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. 2015 Jan 28;2015(1):CD010632. doi: 10.1002/14651858.CD010632.pub2

2. Criteria for the diagnosis of mild cognitive impairment.

Petersen 1999

  1. Memory complaint, preferably corroborated by an informant.

  2. Impaired memory function compared for age and education.

  3. Preserved general cognitive function.

  4. Intact activities of daily living.

  5. Not demented.

Petersen 2004
 
4 subtypes of MCI were identified:

  1. Amnesic mild cognitive impairment, single domain – isolated memory impairment of more than 1.0 SD compared with the age‐ and education‐specific norms, and no difficulty in any other area of cognitive functioning.

  2. Amnesic mild cognitive impairment, multiple domain – 2 or more cognitive domains are impaired, 1 of which is memory impairment (impairment of more than 1.0 SD below the mean of the respective age‐ and education‐matched population).

  3. Non‐amnesic mild cognitive impairment, single domain – impairment in a single domain other than memory of more than 1.0 SD.

  4. Non‐amnesic mild cognitive impairment, multiple domains – impairments in 2 or more domains of more than 1.0 SD but no memory impairment.


 
All 4 subtypes of mild cognitive impairment also have to meet the following criteria:
a)  the presence of a complaint about memory – participants or informants (or both) reporting memory impairment.
b)  intact ability to perform activities of daily living – forgetfulness not compromising overall functional ability; impairment owing to physical disease not sufficient for exclusion.
c)   absence of dementia – assessed by DSM–IV criteria.
 
Morris 1993
 
Clinical Dementia Rating (CDR) is a scale used to classify patients along a continuum from normal aging through Alzheimer’s disease. This scale describes a continuum from normal (CDR 0) through questionable dementia or MCI (CDR 0.5) to mild (CDR 1), moderate (CDR 2), and severe (CDR 3) dementia.
 
Patient's cognitive and functional performances are assessed in 6 areas: memory, orientation, judgement and problem solving, community affairs, home and hobbies, and personal care. Scores in each of these areas are combined to obtain the total score.

MCI: mild cognitive impairment