3. Demographic and participant characteristics of participants included in analysis.
| Study | N / n (included in analysis) | Age converters (non‐converters) |
Gender (M %) |
MMSE score converters (non‐converters) |
APOE Ɛ4 carrier (%) | MCI diagnostic criteria | Sampling | Sources of referral |
Sources of recruitment (setting) |
|
Anchisi 2005 (Italy) |
67/48 | 71.1 ± 73.9 (65.0 ± 9.0) |
25 (52.1) | 26.6 ± 1.7 (28.4 ± 1.1) |
Not reported | Patterson 2010 | Consecutive sample (email from the author on 22nd October 2013) |
GP surgeries (email from the author on 22nd October 2013) |
Outpatients from 4 University Departments (Milan, Brescia, Cologne and Dresden) (email on 22nd October 2013) |
|
Arnáiz 2001 (Sweden) |
20/20 | 64.9 ± 8.3 (60.1 ± 8.4) |
12 (60.0) | 26.7 ± 1.8 (27.2 ± 2.9) |
Not reported | Global Deterioration Scale | Consecutive sample | Not reported | Geriatric University clinic |
|
Berent 1999 (USA) |
20/20 | 70.2 ± 5.5 Total sample |
13 (65.0) | 26.0 ± 1.9 Total sample |
Not reported | AAMI criteria |
Not reported |
Not reported | Cognitive disorders University clinic |
|
Chételat 2003 (France) |
19/17 | 73.0 ± 5.1 (67.8 ± 7.0) |
8 (45.2) | 26.3 ± 1.0 (27.8 ± 1.2) |
Not reported | Petersen 2001 | Not reported |
Not reported | Not reported |
|
Clerici 2009 (Italy) |
30/26 | 74.2 ± 6.9 Total sample |
10 (33.3) | 26.2 ± 1.7 Total sample |
Not reported | Petersen 2004 and CDR = 0.5 criteria | Not reported |
GP surgeries or specialists (85%) or self referral (15%) | University Centre for Research and Treatment |
|
Drzezga 2005 (Germany) |
30/30 | 74.7 ± 4.7 (67.6 ± 2.0) |
14 (46.7) | 25.9 ± 2.1 (27.6 ± 1.5) |
17 (56.7) | Petersen 1999 and CDR = 0.5 criteria | Not reported |
GP surgeries or specialists or other institutions |
University Research Unit |
|
Fellgiebel 2007 (Germany) |
16/16 | 69.5 ± 7.9 (68.8 ± 10.0) |
9 (56.2) | 24.3 ± 1.5 (27.3 ± 1.8) |
Not reported | Petersen 1999 | Consecutive sample | Not reported | University memory clinic |
|
Galluzzi 2010 (Italy) |
90/38 | 72.0 ± 7.1 Total sample |
37 (41.1) | 26.1 ± 1.8 Total sample |
35 (38.9) | Petersen 1999 | Consecutive sample | Not reported | Outpatient memory clinic |
|
Herholz 2011 (USA) ADNI participants |
94/94 | 75.0 ± 7.6 Total sample |
66 (70.2) | 2671 ± 1.6 Total sample |
Not reported |
Petersen 2010 & CDR = 0.5 |
Not reported |
Not reported | Multicentre (not specified) |
|
Landau 2010 (USA) ADNI participants |
85/85 | 78.3 ± 7.5 (78.0 ± 7.4) |
56 (65.9) | 26.4 ± 1.7 (27.3 ± 1.6) |
25 (29.4) | Petersen 2010 & CDR=0.5 |
Not reported |
Not reported | Multicenter (not specified) |
|
Mosconi 2004 (Italy) |
37/37 | 69.0 ± 4.0 (63.0 ± 8.0) |
17 (45.9) | 23.9 ± 1.7 (28.1 ± 1.6) |
16 (43.2) | Petersen 2010 | Not reported |
Not reported | Not reported |
|
Nobili 2008 (Italy) |
36/33 | 77.3 ± 4.8 (74.6 ± 5.4) |
13 (39.4) | 69.0 ± 4.0 (63.0 ± 8.0) |
Not reported on all MCI included in analysis | Petersen 2004 | Not reported |
Not reported | Outpatients |
|
Ossenkoppele 2012a (Netherlands) |
15/12 | 67.0 ± 7.0 Sample analysed |
9 (75%) Sample analysed |
75.0 ± 7.6 Sample analysed |
8 (66.7) Sample analysed |
Petersen 1999 | Not reported |
Not reported |
Not reported |
|
Ossenkoppele 2012b (Netherlands) |
30/12 | 64.0 ± 9.0 Total sample |
23 (30.4) Total sample |
75.0 ± 7.6 Total sample |
Not reported | Petersen 2001 | Not reported |
Not reported |
Outpatient University memory clinic |
|
Pardo 2010 (USA) |
19/18 Reader 1 19/19 Reader 2 |
Mean 80.0 (range 54 ‐ 83) Total sample |
Not reported | Not reported | Not reported | Petersen 1999 | Not reported |
Not reported | Geriatric, Research, Education and Medical Centre Unclear |
|
Schmand 2012 (Netherlands) ADNI participants |
89/89 | Not reported on the sample with ¹⁸F‐FDG scan (N = 89) | Not reported on the sample with ¹⁸F‐FDG scan (N = 89) | Not reported on the sample with ¹⁸F‐FDG scan (N = 89) | Not reported on the sample with ¹⁸F‐FDG scan (N = 89) |
Petersen 2010 & CDR = 0.5 |
Not reported |
Not reported | Multicentre (not specified) |
ADNI: Alzheimer's Disease neuroimaging initiative