Category | Review Question | Inclusion Criteria |
Patients | Participants with mild cognitive impairment, no dementia | Participants fulfilling the criteria for the clinical diagnosis of MCI at baseline |
Index Test | ¹⁸F‐FDG PET biomarker | ¹⁸F‐FDG PET biomarker |
Target Condition | Alzheimer’s disease dementia (conversion from MCI to Alzheimer’s disease dementia) Any other forms of dementia (conversion from MCI to any other forms of dementia) |
Alzheimer’s disease dementia (conversion from MCI to Alzheimer’s disease dementia) Any other forms of dementia (conversion from MCI to any other forms of dementia) |
Reference Standard | NINCDS‐ADRDA; DSM; ICD; McKeith criteria; Lund criteria; NINDS‐ARIEN criteria | NINCDS‐ADRDA; DSM; ICD; McKeith criteria; Lund criteria; NINDS‐ARIEN criteria |
Outcome | N/A | Data to construct 2 x 2 table |
Study Design | N/A | Longitudinal cohort studies and nested case‐control studies if they incorporate a delayed verification design (case‐control nested in cohort studies) |