Figure 2. Association of FADS1/2 rs174547 With Aortic Stenosis (AS) in the Discovery and Replication Cohorts.
For rs174547, C and T are the minor and major alleles, respectively. The sizes of the dark blue squares reflect the weight of the cohorts in the fixed-effects meta-analysis. BioVU indicates Vanderbilt DNA Biobank; EPIC-Norfolk, European Prospective Investigation of Cancer and Nutrition–Norfolk; GERA, Genetic Epidemiology on Adult Health and Aging; MDCS, Malmö Diet and Cancer Study; NA, not applicable; OR, odds ratio; PMBB, Penn Medicine BioBank; and QUEBEC-CAVS, Quebec City Case-Control Calcific Aortic Valve Stenosis.