Table 1. Sample Sizes and Rates of Bipolar Disorder, Major Depression, Nonaffective Psychosis, and Schizophrenia .
| Variable | Family category | |||
|---|---|---|---|---|
| Intact | Not-lived-with father | Stepfather | Adoptive | |
| Sample size of offspring, No. | 2 175 259 | 152 436 | 73 785 | 15 624 |
| Year of birth (offspring), percentile | ||||
| 25th | 1966 | 1969 | 1969 | 1959 |
| 50th | 1974 | 1976 | 1975 | 1963 |
| 75th | 1982 | 1983 | 1981 | 1967 |
| Bipolar disorder, No. (%) | ||||
| Offspring | ||||
| Total | 16 898 (0.8) | 2182 (1.4) | 980 (1.3) | 224 (1.4) |
| Male | 6460 (0.6) | 751 (1.0) | 332 (0.9) | 94 (1.1) |
| Female | 10 438 (1.0) | 1431 (1.9) | 648 (1.8) | 130 (1.8) |
| Biological mother | 16 202 (0.7) | 2339 (1.5) | 847 (1.2) | 248 (1.6) |
| Biological father | 12 044 (0.6) | 1626 (1.1) | NA | 92 (1.0) |
| Stepmother or adoptive mother | NA | NA | NA | 106 (0.7) |
| Stepfather or adoptive father | NA | NA | 476 (0.7) | 65 (0.4) |
| Major depression, No. (%) | ||||
| Offspring | ||||
| Total | 239 918 (11.0) | 26 638 (17.5) | 11 873 (16.10 | 2470 (15.8) |
| Male | 86 591 (7.7) | 9872 (12.8) | 4275 (11.50 | 953 (11.5) |
| Female | 153 327 (14.7) | 16 766 (22.3) | 7598 (20.8) | 1517 (20.6) |
| Biological mother | 263 927 (12.1) | 30 377 (19.9) | 12 825 (17.4) | 1900 (12.3) |
| Biological father | 147 446 (6.8) | 14 261 (9.4) | NA | 591 (6.3) |
| Stepmother or adoptive mother | NA | NA | NA | 1920 (12.3) |
| Stepfather or adoptive father | NA | NA | 5756 (7.8) | 913 (5.8) |
| Nonaffective psychosis, No. (%) | ||||
| Offspring | ||||
| Total | 12 136 (0.6) | 1641 (1.1) | 607 (0.8) | 209 (1.3) |
| Male | 6772 (0.6) | 986 (1.3) | 339 (0.9) | 105 (1.3) |
| Female | 5364 (0.5) | 655 (0.9) | 268 (0.7) | 104 (1.4) |
| Biological mother | 13 114 (0.6) | 2068 (1.4) | 485 (0.7) | 411 (2.7) |
| Biological father | 7868 (0.4) | 2079 (1.4) | NA | 120 (1.3) |
| Stepmother or adoptive mother | NA | NA | NA | 132 (0.8) |
| Stepfather or adoptive father | NA | NA | 284 (0.4) | 56 (0.4) |
| Schizophrenia, No. (%) | ||||
| Offspring | ||||
| Total | 5091 (0.2) | 668 (0.4) | 205 (0.3) | 126 (0.8) |
| Male | 3430 (0.3) | 477 (0.6) | 140 (0.4) | 75 (0.9) |
| Female | 1661 (0.2) | 191 (0.3) | 65 (0.2) | 51 (0.7) |
| Biological mother | 2383 (0.1) | 477 (0.3) | 85 (0.1) | 359 (2.3) |
| Biological father | 1489 (0.1) | 1052 (0.7) | NA | 71 (0.8) |
| Stepmother or adoptive mother | NA | NA | NA | 12 (0.1) |
| Stepfather or adoptive father | NA | NA | 76 (0.1) | 11 (0.1) |
Abbreviation: NA, not applicable.