Table 1.
Demographic, clinical and genetic data in patients with schizophrenia and healthy controls.
| Variable | SCZ (n = 957) | HC (n = 576) | F or χ2 (p) |
|---|---|---|---|
| Gender(male/female), n | 783/174 | 263/313 | 216.8 (<0.001) |
| Age (years) | 47.8 ± 10.2 | 45.8 ± 12.8 | 11.7 (<0.01) |
| Education (years) | 9.3 ± 6.4 | 8.7 ± 3.2 | 1.5 (0.09) |
| Smokers/Non-smokers, n | 627/318 | 218/358 | 117.7 (<0.000) |
| BMI (kg/m2) | 24.5 ± 3.9 | 25.1 ± 3.9 | 2.7 (<0.01) |
| Drinkers/Non-drinkers, n | 137/727 | 121/455 | 6.2 (0.013) |
| MTHFR genotype distribution | 2.0 (0.36) | ||
| CC n(%) | 298 (38.9) | 145 (34.8) | |
| CT n(%) | 344 (45.0) | 202 (48.4) | |
| TT n(%) | 123 (16.1) | 70 (16.8) | |
| MTHFR allele frequency | |||
| C/T, n | 590/940 | 342/492 | 0.08 (0.83) |
Note: Data is given as mean ± standard deviation; BMI = body mass index; SCZ = schizophrenia; HC = healthy control; MTHFR = Methylenetetrahydrofolate reductase.