Table 3.
Multiple logistic regression analysis of the MTHFR Ala222Val polymorphism and suicide susceptibility.
| Genotype | Attempers n = 125 | Nonattempters n = 642 | p-valuea | Crude OR (95% CI) | Adjusted OR (95% CI) | p-valueb |
|---|---|---|---|---|---|---|
| MTHFR Ala222Val (HWE = 0.791) | ||||||
| Val/Val | 26 | 99 | 1 | 1 | ||
| Ala/Val | 45 | 299 | 0.039 | 0.61 (0.35–1.01) | 0.36 (0.23–0.59) | 0.0000 |
| Ala/Ala | 54 | 244 | 0.52 | 1.10 (0.64–1.87) | 0.97 (0.73–1.28) | 0.83 |
Notes: aChi-squared tests were used to determine differences in genotype distributions between attempters and nonattempters.
bAdjusted for age, gender, smoking, BMI, drinking and marital status.