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. 2020 Mar 19;10:5073. doi: 10.1038/s41598-020-61758-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Global comparison of Arabidopsis Col-0 and Mediator mutant transcriptomes in control and abiotic stress conditions. Each data point represents the entire transcriptome for each sample, and are arranged in the first, second and third dimensions according to the components of a principal component analysis (PCA; shown on the x, z and y axes, respectively). Each transcriptome from the (A) heat, (B) cold and (C) salt stress experiments is shown as one data point. Transcriptomes from plants in control conditions are shown as squares; those from early stress time-points (HS30, CS3 and SS4) are shown as triangles; and those from late time-points (HS120, CS72 and SS24) are shown as circles. Col-0 wild type: black; med9: green; med16: cyan; med18: red; cdk8: orange. The contribution of each component to the total variation between samples is shown as a percentage. (D-F) Total numbers of significant differentially expressed genes (DEGs; p_adj ≤ 0.01 and log₂ fold-change ≥ ± 0.5) between Col-0 and Mediator mutant transcriptomes in each stress.