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. 2020 Mar 19;10:5062. doi: 10.1038/s41598-020-61992-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Maximal clonal immunogenicity (inverse tumor fitness), Ϊ, was found to be uncorrelated with measures of expression-based tumor immune response (TIL burden, TIL clonality, and CYT) and TMB in both (A) NSCLC, (B) SKCM patients. Several of the immune measures were found to be highly correlated with each other in both TCGA patient sets. Values in each circle indicate the Spearman correlations between the features, with color and size representative of correlation strength. Tiles with no color indicate a non-significant (p > 0.05) correlation between features.