| Group | Morning dose | Midday dose | Evening dose |
| 1 | full daily HC dose | placebo | placebo |
| 2 | 2/3 full daily HC dose | placebo | 1/3 full daily HC dose |
| 3 | 1/3 full daily HC dose | 1/3 full daily HC dose | 1/3 full daily HC dose |
| 4 | 1/3 full daily HC dose | placebo | 2/3 full daily HC dose |
| 5 | placebo | placebo | full daily HC dose |
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