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. 2020 Mar 19;2020(3):CD012517. doi: 10.1002/14651858.CD012517.pub2

Silva 1994.

Methods RCT.
Location: Brazil.
Duration: not defined.
Participants 13 participants.
Age: children < 16 years.
Gender split: not stated.
Diagnosis: CAH due to 21OH deficiency.
Interventions HC 20 mg/m² per day in divided doses.
Arm 1: higher morning dose (n = 7).
Arm 2: higher evening dose (n = 6).
Outcomes 17 OHP, testosterone and androstenedione at the following time points: ‐24 h, baseline, 2 h, 4 h, and 6 h.
Notes The full article summarizing the results is not available.

17 OHP: 17‐hydroxyprogesterone
 CAH: congenital adrenal hyperplasia
 HC: hydrocortisone
 RCT: randomised controlled trial