Table 2.
Clinical Characteristicsa
| Characteristics | VBC-CAP (n = 57) | V-CAP (n = 98) | B-CAP (n = 968) | P Value |
|---|---|---|---|---|
| Days from onset of symptoms to admission (median, IQR) | 4 (3–7) | 5 (3–7) | 4 (2–7) | .017 |
| Clinical Manifestations | ||||
| Axillary temperature ≥38ºC | 31 (54.4%) | 54 (55.1%) | 757 (43.0%) | .017 |
| Previous URTI | 15 (26.3%) | 35 (35.7%) | 294 (30.5%) | .766 |
| Chills | 21 (36.8%) | 29 (29.6%) | 368 (38.1%) | .249 |
| Diarrhea/vomiting | 7 (12.3%) | 25 (25.5%) | 202 (20.9%) | .148 |
| Cough | 56 (98.2%) | 95 (96.9%) | 833 (86.1%) | <.001 |
| Purulent sputum | 36 (63.20%) | 34 (37%) | 435 (46.7%) | .008 |
| Chest pain | 15 (26.3%) | 15 (15.3%) | 351 (36.3%) | <.001 |
| Dyspnea | 40 (70.20%) | 73 (74.5%) | 660 (68.2%) | .427 |
| Headache | 7 (12.30%) | 17 (17.3%) | 136 (14.0%) | .612 |
| Myalgia | 29 (50.9%) | 54 (55.10%) | 176 (18.2%) | <.001 |
| Confusion | 3 (5.3%) | 5 (5.1%) | 170 (17.6%) | <.001 |
| Septic shock at presentation | 6 (10.5%) | 7 (12.1%) | 63 (9.1%) | .028 |
| Radiological Findings | ||||
| Multilobular involvement | 3 (5.3%) | 7 (7.1%) | 222 (12.6%) | .047 |
| Bilateral pulmonary infiltrates | 20 (35.1%) | 31 (31.6%) | 363 (20.6%) | <.001 |
| Interstitial pattern | 5 (8.8%) | 32 (32.7%) | 31 (1.8%) | <.001 |
| Unilobular pulmonary infiltrates | 28 (49%) | 28 (28.6%) | 1159 (65.8%) | <.001 |
| Pleural effusion | 8 (14%) | 7 (7.2%) | 277 (15.7%) | .073 |
| Laboratory Findings | ||||
| Respiratory insufficiency | 38 (67.9%) | 58 (63.73%) | 504 (59.7%) | .163 |
| Leukocytes (×109/L) | 9.6 (5.55–14.95) | 7.0 (4.7–10.92) | 12.8 (9.15–18.10) | <.001 |
| Neutrophils (×109/L) | 83.6% (78.75–88.25%) | 81.55% (72.55–86.97) | 84% (77.4%–88%) | .018 |
| SAPS ≥6 | 11 (19.3%) | 15 (15.3%) | 306 (31.6%) | .001 |
| PSI score ≥4 | 23 (40.4%) | 40 (40.8%) | 651 (67.3%) | <.001 |
| CURB-65 score ≥2 | 25 (43.9%) | 42 (42.9%) | 675 (69.7%) | <.001 |
Abbreviations: B-CAP, bacterial community-acquired pneumonia; IQR, interquartile range; PSI, pneumonia severity index for adult; SAPS, simplified acute physiology score; URTI, upper respiratory tract infection; V-CAP, viral CAP; VBC-CAP, viral and bacterial coinfection CAP.
aProportions were calculated as percentages of patients with available data.