Table 4. Weight Gain/Loss in Dams Receiving Valproic Acid in Combination with Antioxidants from Day 7 to Day 17 of Gestation and Weights on Alternative Days Are Mentioned as Days 1(7), 2(9), 3(11), 4(13), 5(15), and 6(17)a.
| maternal weight variation (g) | ||||||
|---|---|---|---|---|---|---|
| treatment groups | day 1 | day 2 | day 3 | day 4 | day 5 | day 6 |
| N.C | 170 ± 8.5 | 177 ± 7.98 | 182 ± 7.41 | 182 ± 6.41 | 187 ± 7.00 | 193 ± 6.41 |
| D.C V.P (500 mg/kg) | 180 ± 7.4 | 176 ± 7.42 | 189 ± 7.09 | 190 ± 7.64 | 188 ± 7.21 | 176 ± 5.51 |
| V.P + Vit. C (500 mg + 2000 mg/kg) | 165 ± 5.64 | 166 ± 2.00 | 184 ± 7.07 | 184 ± 7.07 | 196 ± 8.77 | 196 ± 8.77 |
| V.P + Vit. C (500 mg + 8000 mg/kg) | 158 ± 4.85 | 171 ± 4.72 | 166 ± 4.64 | 171 ± 5.95 | 182 ± 9.6 | 179 ± 27.81 |
| V.P + Se (500 mg + 100 μg/kg) | 144 ± 2.5 | 145 ± 1.26 | 114 ± 19.56*** | 119 ± 20.81*** | 127 ± 22.8** | 107 ± 29.4*** |
| V.P + Se (500 mg + 200 μg/kg) | 175 ± 2.31 | 196 ± 2.62 | 177 ± 3.33 | 173 ± 4.62 | 171 ± 4.27 | 165 ± 4.37 |
| V.P + G.S (500 mg + 300 mg/kg) | 147 ± 5.7 | 156 ± 2.35 | 169 ± 3.30 | 173 ± 3.17 | 175 ± 3.15 | 178 ± 3.88 |
| V.P + G.S (500 mg + 600 mg/kg) | 141 ± 5.46 | 158 ± 6.48 | 164 ± 7.38 | 144 ± 24.33* | 144 ± 24.41* | 149 ± 25.13 |
a
Data are represented as mean ± SEM, n = 10;*P < 0.05, **P < 0.01, ***P < 0.001maternal weight in comparison to day 1 of valproic acid administration.