Figures 1–4.

Infectious necrotic hepatitis. Figure 1. Multiple, well-demarcated, randomly distributed, pale foci of necrosis in an ovine liver. Reproduced with permission from Navarro and Uzal, 2016.⁴⁴ Figure 2. Large focus of coagulative necrosis in an equine liver, with an inflammatory cell rim. H&E. Figure 3. Higher amplification of the boxed area in Fig. 2. Large numbers of rod-shaped bacteria at the periphery of the necrotic area (at right), with a contiguous leukocytic infiltrate of viable and degenerate neutrophils (at left). H&E. Figure 4. Numerous immunopositive Clostridium novyi at the periphery of a necrotic hepatic focus. Indirect immunoperoxidase staining, as described in Nyaoke et al. 2018.⁴⁸