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. 2019 Jul 26;35:11. doi: 10.1186/s42826-019-0010-4

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Gene expression patterns of muscle-related target genes following BoNT/A muscle injection in ICR mice from three different sources. a–g qRT-PCR comparing negative control groups and BoNT/A treated groups. Expression levels of collagen type 1 (Col1a1), interleukin 6 (Il-6), transforming growth factor beta 1 (Tgf-b1), matrix metallopeptidase (Mmp-2), myosin heavy chain IIa (MhcIIa), myosin heavy chain IIb (MhcIIb), and myosin heavy chain IIx (MhcIIx) were analyzed. *Significantly different compared to the negative control group (*p < 0.05). The data represent the mean ± SD of three replicates