Table 2.
Hematological analysis of Korl:ICR, A:ICR and B:ICR with BoNT/A muscle treatment
| Parameters/Groups | Con-Korl:ICR | Treated-Korl:ICR | Con-A:ICR | Treated-A:ICR | Con-B:ICR | Treated-B:ICR |
|---|---|---|---|---|---|---|
| No. of animals | 10 | 10 | 10 | 10 | 10 | 10 |
| RBC (106/ul) | 10.55 ± 0.44 | 9.10 ± 0.27** | 10.50 ± 0.25 | 8.61 ± 0.58** | 10.72 ± 0.24 | 8.72 ± 0.25** |
| HGB (g/dl) | 15.67 ± 0.71 | 14.67 ± 0.58** | 15.58 ± 0.33 | 13.98 ± 0.75** | 15.79 ± 0.44 | 14.26 ± 0.36** |
| HCT (%) | 50.93 ± 1.77 | 47.94 ± 1.76** | 49.21 ± 1.04 | 46.15 ± 2.61** | 50.55 ± 1.13 | 46.44 ± 1.07** |
| MCV (fL) | 48.32 ± 0.92 | 52.70 ± 1.47** | 46.88 ± 0.40 | 53.61 ± 1.36** | 47.16 ± 0.37 | 53.30 ± 1.40** |
| MCH (pg) | 14.86 ± 0.20 | 16.14 ± 0.66** | 14.84 ± 0.16 | 16.26 ± 0.58** | 14.72 ± 0.14 | 16.28 ± 0.37** |
| MCHC (g/dl) | 30.79 ± 0.79 | 30.64 ± 0.68 | 31.64 ± 0.35 | 30.31 ± 0.45** | 31.25 ± 0.38 | 30.69 ± 0.41** |
| PLT (103/ul) | 1117.70 ± 134.98 | 1276.30 ± 184.56 | 1065.00 ± 200.56 | 1505.10 ± 179.39** | 1107.60 ± 122.23 | 1275.50 ± 193.77** |
| WBC (103/ul) | 2.23 ± 0.85 | 2.58 ± 0.80 | 2.62 ± 0.77 | 4.98 ± 1.28** | 1.48 ± 0.28 | 3.38 ± 1.11** |
| WBC Diffrential count | ||||||
| Neutrophil (103/ul) | 0.33 ± 0.09 | 0.43 ± 0.14 | 0.37 ± 0.08 | 0.74 ± 0.51 | 0.25 ± 0.05 | 0.51 ± 0.13 |
| Lymphocyte (103/ul) | 1.57 ± 0.48 | 1.94 ± 0.64 | 2.11 ± 0.65 | 3.95 ± 1.27** | 1.15 ± 0.16 | 2.59 ± 0.87 |
| Monocyte (103/ul) | 0.03 ± 0.01 | 0.05 ± 0.02 | 0.04 ± 0.01 | 0.08 ± 0.02** | 0.03 ± 0.01 | 0.08 ± 0.02 |
| Eosinophil (103/ul) | 0.05 ± 0.02 | 0.12 ± 0.06 | 0.07 ± 0.02 | 0.13 ± 0.09 | 0.06 ± 0.01 | 0.14 ± 0.18 |
| Basophil (103/ul) | 0.01 ± 0.01 | 0.02 ± 0.01 | 0.01 ± 0.01 | 0.02 ± 0.01** | 0.01 ± 0.01 | 0.02 ± 0.01 |
| Neutrophil (%) | 15.98 ± 4.76 | 17.09 ± 4.87 | 14.42 ± 1.43 | 15.19 ± 9.47 | 16.89 ± 2.74 | 15.87 ± 4.26** |
| Lymphocyte (%) | 72.13 ± 10.14 | 74.57 ± 4.76 | 79.99 ± 2.02 | 78.71 ± 9.55 | 77.60 ± 11.75 | 76.14 ± 4.41** |
| Monocyte (%) | 1.40 ± 0.70 | 2.05 ± 0.50 | 1.48 ± 0.24 | 1.58 ± 0.43 | 1.80 ± 0.88 | 2.32 ± 0.31** |
| Eosinophil (%) | 2.31 ± 1.46 | 4.40 ± 1.86 | 2.68 ± 0.45 | 2.94 ± 2.32 | 4.02 ± 1.66 | 3.65 ± 3.10 |
| Basophil (%) | 0.55 ± 0.28 | 0.58 ± 0.29 | 0.47 ± 0.22 | 0.48 ± 0.18 | 0.79 ± 0.36 | 0.60 ± 0.25 |
| Reti (103/ul) | 339.60 ± 30.29 | 318.06 ± 148.94 | 341.60 ± 25.56 | 331.18 ± 58.50 | 325.71 ± 28.23 | 355.47 ± 53.07 |
| Reti (%) | 3.23 ± 0.37 | 3.51 ± 1.65 | 3.26 ± 0.27 | 3.88 ± 0.87 | 3.04 ± 0.20 | 3.84 ± 0.55** |
The data shown represent the mean ± SD (n = 10/group)
*Significantly different from the negative control group (*p < 0.05, **p < 0.01)