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. 2020 Mar 18;6:5. doi: 10.1186/s40780-020-00159-7

Table 1.

Clinical characteristics of study patients

Characteristics Repaglinide and clopidogrel group Mitiglinide and clopidogrel group Repaglinide group p value
(N = 15) (N = 15) (N = 15)
Age 75.6 ± 12.2 70.4 ± 11.5 76.1 ± 10.9 0.332*
Male (%) 10 (66.7%) 12 (80.0%) 10 (66.7%) 0.649***
BMI 23.6 ± 3.2 24.4 ± 2.9 23.2 ± 3.9 0.598*
HbA1c 9.3 ± 2.0 9.5 ± 2.0 9.7 ± 2.6 0.851*
Serum creatinine 0.84 ± 0.32 0.80 ± 0.16 0.76 ± 0.16 0.594*
Liver function (Grade 1 [CTCAE ver.4.0]: AST, ALT, or T-Bil) 4 (26.7%) 5 (33.3%) 3 (20.0%) 0.912**
Calorie intake (kcal) 1325.9 ± 283.3 1497.0 ± 247.5 1517.2 ± 168.7 0.065*
Concomitant agent use (oral hypoglycemic drugs, insulin, GLP-1 agonists, and/or agents which may enhance the hypoglycemic action of repaglinide or mitiglinide, other than the above) 10 (67.7%) 9 (60.0%) 9 (60.0%) 0.910***

Mean ± S.D., * One-way analysis of variance, ** Fisher’s exact test, *** Chi-square test