Table 1.
Results for grade of lens opacity according to anaesthetic dose and ocular surface condition in the absence or presence of infrared light exposure in anaesthetised C57BL/6 N mice
Without infrared light exposure | With infrared light exposure | |||||||
---|---|---|---|---|---|---|---|---|
80% anaesthetic dose | 120% anaesthetic dose | 80% anaesthetic dose | 120% anaesthetic dose | |||||
Wet ocular surface (n = 4) |
Dry ocular surface (n = 4) |
Wet ocular surface (n = 5) |
Dry ocular surface (n = 4) |
Wet ocular surface (n = 3) |
Dry ocular surface (n = 3) |
Wet ocular surface (n = 3) |
Dry ocular surface (n = 3) |
|
10 min after anaesthesia | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 |
15 min after anaesthesia | 1.25 ± 0.43 | 1.25 ± 0.43 | 1.00 ± 0.00 | 1.25 ± 0.43 | 1.00 ± 0.00 | 1.33 ± 0.47 | 1.00 ± 0.00 | 1.00 ± 0.00 |
20 min after anaesthesia | 1.25 ± 0.43 | 3.25 ± 0.83* | 1.00 ± 0.00 | 3.50 ± 1.12* | 1.00 ± 0.00 | 4.00 ± 0.82* | 1.00 ± 0.00 | 4.66 ± 0.47* |
25 min after anaesthesia | 1.25 ± 0.43 | 4.50 ± 0.87* | 1.20 ± 0.40 | 5.25 ± 0.43* | 1.00 ± 0.00 | 6.00 ± 0.00* | 1.33 ± 0.47 | 6.00 ± 0.00* |
30 min after anaesthesia | 1.25 ± 0.43 | 5.75 ± 0.43* | 1.20 ± 0.40 | 5.75 ± 0.43* | 1.00 ± 0.00 | 6.00 ± 0.00* | 1.33 ± 0.47 | 6.00 ± 0.00* |
Results are expressed as mean ± standard deviation
*p < 0.05 when compared with wet ocular surface in each condition