Table 4.

Significant GO biological processes and KEGG pathways

Category	Term	Count of genes	P-value
Biology Process	Cellular metal ion homeostasis	12	6.570 × 10− 05
	Metal ion homeostasis	12	9.840 × 10−05
	Cellular cation homeostasis	13	1.590 × 10−04
	Cellular calcium ion homeostasis	11	1.760 × 10− 04
	Calcium ion homeostasis	11	2.200 × 10−04
	Cellular di-, tri-valent inorganic cation homeostasis	12	2.410 × 10−04
	Di-, tri-valent inorganic cation homeostasis	12	3.740 × 10−04
	Cell-cell signaling	20	4.350 × 10−04
	Cation homeostasis	13	4.710 × 10−04
	Regulation of system process	13	9.290 × 10−04
	Ectoderm development	10	1.434 × 10−03
	Cellular ion homeostasis	13	4.521 × 10− 03
	Cellular chemical homeostasis	13	5.122 × 10−03
	Chemical homeostasis	15	8.944 × 10−03
	Ion homeostasis	13	8.989 × 10−03
	Response to wounding	15	1.186 × 10−02
	Cellular homeostasis	13	2.288 × 10−02
	Behavior	13	2.390 × 10− 02
	Multicellular organism reproduction	13	3.075 × 10−02
	Reproductive process in a multicellular organism	13	3.075 × 10−02
	Defense response	15	3.669 × 10−02
	Gamete generation	11	3.984 × 10−02
	Homeostatic process	17	4.436 × 10−02
	G-protein coupled receptor protein signaling pathway	23	4.513 × 10−02
	Transmission of nerve impulse	10	4.589 × 10−02
KEGG Pathway	Neuroactive ligand-receptor interaction	9	7.151 × 10−04
	Tight junction	4	1.892 × 10−02
	Wnt signaling pathway	4	2.391 × 10−02
	Calcium signaling pathway	4	3.157 × 10−02
	Cytokine-cytokine receptor interaction	5	3.380 × 10−02

Count of genes, the total number of genes significantly involved in a GO biological process or pathway; GO, gene ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes pathway enrichment