TABLE 4.
Unadjusted 2- and 10-week mortality outcomes for the five combination treatment regimens in the Advancing Cryptococcal Treatment in Africa trial.
Regimen | 2-week mortality |
10-week mortality |
||||
---|---|---|---|---|---|---|
n/N | % | 95% CI | n/N | % | 95% CI | |
One-week amphotericin B and flucytosine (short course) | 13/113 | 11.6 | 5.7–17.5 | 27/113 | 24.2 | 16.2–32.1 |
Two-week fluconazole and flucytosine (all-oral regimen) | 41/225 | 18.2 | 13.2–23.3 | 79/225 | 35.1 | 28.9–41.3 |
Two-week amphotericin B and flucytosine | 24/115 | 20.9 | 13.4–28.3 | 44/115 | 38.3 | 29.4–47.2 |
Two-week amphotericin B and fluconazole | 25/114 | 21.9 | 14.3–29.5 | 47/114 | 41.3 | 32.3–50.4 |
One-week amphotericin B and fluconazole | 36/111 | 32.4 | 23.7–41.1 | 54/111 | 48.6 | 39.4–57.9 |
CI, confidence interval; n/N, number of deaths divided by number of participants in that trial arm.