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. 2019 Nov 8;20(1):1030. doi: 10.4102/sajhivmed.v20i1.1030

TABLE 4.

Unadjusted 2- and 10-week mortality outcomes for the five combination treatment regimens in the Advancing Cryptococcal Treatment in Africa trial.

Regimen 2-week mortality
10-week mortality
n/N % 95% CI n/N % 95% CI
One-week amphotericin B and flucytosine (short course) 13/113 11.6 5.7–17.5 27/113 24.2 16.2–32.1
Two-week fluconazole and flucytosine (all-oral regimen) 41/225 18.2 13.2–23.3 79/225 35.1 28.9–41.3
Two-week amphotericin B and flucytosine 24/115 20.9 13.4–28.3 44/115 38.3 29.4–47.2
Two-week amphotericin B and fluconazole 25/114 21.9 14.3–29.5 47/114 41.3 32.3–50.4
One-week amphotericin B and fluconazole 36/111 32.4 23.7–41.1 54/111 48.6 39.4–57.9

CI, confidence interval; n/N, number of deaths divided by number of participants in that trial arm.