TABLE 8.
Laboratory monitoring according to induction regimen used.
| Induction regimen | Week 1 | Week 2 | Laboratory monitoring |
|---|---|---|---|
| Preferred | Amphotericin B deoxycholate + 5-FC | Fluconazole | Day 0: Full blood count and differential, creatinine clearance, potassium, magnesium |
| Day 3: Full blood count (only if low baseline haemoglobin), creatinine clearance, potassium, magnesium | |||
| Day 7: Full blood count and differential, creatinine clearance, potassium, magnesium | |||
| Amphotericin B unavailable | Fluconazole + 5-FC | Fluconazole + 5-FC | Day 0: Full blood count and differential, creatinine clearance |
| Day 3: Full blood count (if low baseline haemoglobin) | |||
| Day 7: Full blood count and differential | |||
| Day 10: Full blood count and differential (if any abnormalities previously) | |||
| Day 14: Full blood count and differential, creatinine clearance can be done more frequently if baseline is abnormal | |||
| 5-FC is unavailable | Amphotericin B deoxycholate + fluconazole | Amphotericin B deoxycholate + fluconazole | Day 0: Creatinine clearance, potassium, magnesium, full blood count |
| Day 3: Creatinine clearance, potassium, magnesium | |||
| Day 7: Creatinine clearance, potassium, magnesium, full blood count | |||
| Day 10: Creatinine clearance, potassium, magnesium | |||
| Day 14: Creatinine clearance, potassium, magnesium, full blood count |