Table 4.

Multivariate logistic regression analysis (Stepwise Forward Wald) for subsequent events of APO with each of the early pregnancy variables in 1163 pregnant women

Variables	Odds ratio	95% CI	Wald	P value
Hcy
I quartile	1	–	–	–
II quartile	1.03	0.74–1.45	0.04	0.852
III quartile	1.26	0.90–1.76	1.82	0.178
IV quartile	5.89	4.08–8.51	89.09	< 0.001
Folate
I quartile	1	–	–	–
II quartile	0.71	0.50–1.00	3.96	0.047
III quartile	0.45	0.32–0.63	21.17	< 0.001
IV quartile	0.35	0.25–0.50	34.14	< 0.001
SBP
I quartile	1	–	–	–
II quartile	1.27	0.90–1.80	1.83	0.176
III quartile	1.30	0.92–1.84	2.19	0.139
IV quartile	1.89	1.33–2.68	12.47	< 0.001
DBP
I quartile	1	–	–	–
II quartile	1.08	0.77–1.52	0.19	0.660
III quartile	1.34	0.95–1.89	2.84	0.092
IV quartile	1.69	1.20–2.38	9.00	0.003
BMI
I quartile	1	–	–	–
II quartile	1.14	0.81–1.60	0.53	0.467
III quartile	1.41	1.00–1.98	3.86	0.049
IV quartile	1.83	1.30–2.58	11.86	0.001
Age
I quartile	1	–	–	–
II quartile	0.88	0.63–1.24	0.54	0.463
III quartile	1.17	0.84–1.65	0.85	0.356
IV quartile	1.52	1.08–2.14	5.75	0.016
Folate supplementation	0.55	0.35–0.86	6.72	0.010

The 15 variables included in the model were as follows: Hcy, folate, VB12, TC, TG, LDL-C, HDL-C, FPG, UA, SBP, DBP, BMI and age, folate supplementation, and VB12 supplementation according to the results of the univariate logistic regression analysis. Of these, VB12, TC, TG, LDL-C, HDL-C, FPG, UA, and VB12 supplementation were rejected by the multivariate logistic regression analysis