Table 1. Purity, Polydispersity Index Values (PDI), and Oligomer Purity (OP) of the Chol-PEGn Derivatives (n.s.: Not Synthesized).
R = OH |
R = OCH3 |
R = RGD |
|||||||
---|---|---|---|---|---|---|---|---|---|
derivatives | compd | purity | PDI/OP | compd | purity | PDI/OP | compd | purity | PDI/OP |
Chol-PEG4-R | 4a | 99% | 1.0/100% | 9 | 99% | 1.0/100% | 13 | 99% | 1.0/100% |
Chol-PEG8-R | 5 | 99% | 1.000052/98.7% | 10 | 99% | 1.000039/98.8% | 14 | 97% | 1.000001/99.9% |
Chol-PEG12-R | 6 | 99% | 1.000007/99.7% | 11 | 99% | 1.000055/98.0% | 15 | 95% | 1.000013/98.4% |
Chol-PEG16-R | 7 | 99% | 1.000009/99.5% | n.s. | 16 | 90% | 1.000045/96.3% | ||
Chol-PEG20-R | 8 | 99% | 1.000023/98.3% | n.s. | 17 | 97% | 1.000019/97.6% |