Table 3.
parameters | baseline | 1 month | 3 month | p value | ||
---|---|---|---|---|---|---|
baseline vs 1 month | baseline vs 3 month | 1 month vs 3 month | ||||
OSDIa | 31.39 ± 8.57 | 28.10 ± 5.88 | 21.58 ± 4.97 | 0.027* | 0.000* | 0.000# |
EMASb | 1.00 (1.00, 2.00) | 1.00 (0.00, 1.25) | 1.00 (0.00, 1.00) | 0.020* | 0.025* | 0.739 |
MGYSSb | 1.00 (1.00, 1.00) | 1.00 (1.00, 1.00) | 1.00 (0.00, 1.00) | 0.414 | 0.020* | 0.467 |
CFSb | 0.00 (0.00, 1.00) | 0.00 (0.00, 1.00) | 0.00 (0.00, 1.00) | 0.577 | 0.589 | 1.000 |
TMHa/mm | 0.18 ± 0.31 | 0.19 ± 0.03 | 0.19 ± 0.02 | 0.210 | 0.147 | 0.611 |
NITBUTa/s | 4.98 ± 1.84 | 5.67 ± 1.80 | 5.87 ± 1.17 | 0.091 | 0.026* | 0.550 |
MGLSb | 1.00 (1.00, 2.00) | 1.00 (1.00, 2.00) | 1.00 (1.00, 1.00) | 0.083 | 0.002* | 0.008# |
OSDI Ocular Surface Disease Index, MGYSS Meibomian gland yielding secretion score, CFS corneal fluorescein staining, TMH tear meniscus height, EMAS Eyelid margin abnormality score, MGLS meibomian gland loss score, TBUS tear film break-up time. a: Normal distribution data, the mean is expressed as Mean ± SD, and the paired sample t test is used for comparison between groups. b: Non-normally distributed data, the mean is represented by Median (P25, P75), and the comparison between groups is based on paired sample nonparametric Wilcoxon test. *p < 0.05 vs Baseline; #p < 0.05 vs 1 month