Table 3.
Maximum increase and maximum decrease of maximum standardised uptake values. (SUVmax) in prostate, lymph node, bone lesions, and normal PSMA-avid organs. SUVmax is presented in proportional change and the time point at which the maximum SUVmax occurred is presented in weeks. Paired organs are analysed as a mean of right and left
| Maximum increase | Maximum decrease | |||||
|---|---|---|---|---|---|---|
| Lesion/normal organ | n | SUVmax (%); mean (range) | Time point (weeks); mean (range) | n | SUVmax (%); mean (range) | Time point (weeks); mean (range) |
| Primary tumour (prostate) | 5 | 29 (6–84) | 4.3 (3.0–4.8) | 11 | − 46 (− 64–(− 4)) | 5.8 (1.0–8.6) |
| Lymph node metastases | 7 | 19 (11–41) | 2.7 (1.0–4.8) | 9 | − 48 (− 86–(− 4)) | 5.2 (1.1–8.7) |
| Bone lesions | 13 | 76 (8–238) | 4.3 (2.5–8.7) | 10 | − 50 (− 77–(− 20)) | 7.7 (2.5–8.7) |
| Parotid glands | 8 | 23 (5–45) | 3.3 (1.1–5.9) | 1 | − 8 | 3.5 |
| Submandibular glands | 8 | 22 (5–49) | 4.1 (1.7–8.5) | 1 | − 14 | 2.5 |
| Sublingual glands | 9 | 15 (8–22) | 2.7 (1.7–4.0) | – | – | – |
| Liver | 9 | 7 (2–13) | 2.8 (0.9–5.9) | – | – | – |
| Spleen | 6 | 16 (2–36) | 4.0 (1.9–8.0) | 3 | − 19 (− 6–(− 14)) | 1.6 (0.8–3.0) |
| Kidneys | 8 | 10 (7–18) | 3.6 (0.8.7.0) | 1 | − 19 | 8.7 |