Table 2.
Baseline patient demographics.
| Patient characteristics | SDDK IV for analgesia (n=210) | Ketamine IM for agitation/delirium (n=37) |
|---|---|---|
| No. of ED encounters | 210 | 37 |
| Age, median (IQR), years | 43 (IQR: 30–54) | 39 (IQR: 31–48) |
| Sex, male (%) | 39 | 70 |
| Weight, median (IQR), kg | 79.9 (65.8–90.7) | 77.1 (IQR: 68–99.8) |
| History of psychosis (%) | 11.9 | 40.5 |
| History of illicit drug use or alcohol abuse (%) | 22.4 | 59.5 |
| Systolic blood pressure, median (IQR), mmHg* | 130 (118–149.5) | N/A |
| Diastolic blood pressure, median (IQR), mmHg* | 81 (71–90.5) | N/A |
| Pulse rate, median (IQR), beats/min* | 83 (IQR: 70–98) | N/A |
| O2 saturation, median (IQR), %* | 98 (IQR: 97–100) | N/A |
| Concomitant medications† (%) | ||
| Antihistamines | 10.0 | 24.3 |
| Antipsychotics | 3.3 | 35.1 |
| Benzodiazepines | 12.4 | 54.1 |
| Opioids | 30.0 | 5.4 |
*
Baseline vitals prior to ketamine administration
†
One hour before or two hours after ketamine administration
SDDK, subdissociative-dose ketamine; IV, intravenous; IM, intramuscular; ED, emergency department; IQR, interquartile range; kg, kilogram; mmHG, millimeters of mercury; O2, oxygen.