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. 2020 Mar 10;26:e921594-1–e921594-15. doi: 10.12659/MSM.921594

Figure 1.

Figure 1

lncRNA MSC-AS1 is upregulated in OS and is associated with poor prognosis. (A) RT-qPCR results showed that lncRNA MSC-AS1 expression was significantly higher in OS tissues than in adjacent normal bone tissues, n=45. (B) Relationship between lncRNA MSC-AS1 expression and prognosis of OS patients was analyzed by Kaplan-Meier assay, n=45. (C) lncRNA MSC-AS1 expression in human normal osteoblast hFOB1.19 cells and OS cell lines were detected by RT-qPCR. The experiments were performed 3 times; compared with normal group/hFOB1.19 cells, ** p<0.05. The independent-samples t test was used for statistical analysis of comparisons in (A), Kaplan-Meier assay was utilized to analyze (B), and one-way ANOVA and Tukey’s multiple comparisons test were applied to determine (C). lncRNA – long non-coding RNA; OS – osteosarcoma; RT-qPCR – reverse transcription-quantitative polymerase chain reaction; ANOVA – analysis of variance.