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. 2020 Mar 10;26:e921594-1–e921594-15. doi: 10.12659/MSM.921594

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© Med Sci Monit, 2020

This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

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Silenced lncRNA MSC-AS1 inhibits OS cell in vivo. (A) Tumor volumes in all groups were calculated every 3 days using the formula V=L×W²×0.5. (B) On the 21^st day, the tumors were taken out and weighed. (C) Ki67-positive expression of tumors in each group was detected by immunohistochemistry. N=6 in each group, compared with the control group, * p<0.05, ** p<0.01. Two-way ANOVA and Tukey’s multiple comparisons test were applied to determine (A), and one-way ANOVA and Tukey’s multiple comparisons test were applied to determine (B, C). lncRNA – long non-coding RNA; OS – osteosarcoma; ANOVA – analysis of variance.