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. Author manuscript; available in PMC: 2020 Oct 15.
Published in final edited form as: J Immunol. 2019 Sep 25;203(8):2063–2075. doi: 10.4049/jimmunol.1900399

Table I.

Patient characteristics and clinical phenotypes following primary CMV infection in D+R-LTRs.

LTR Age (y) Gender Primary Diagnosis Immunosuppression at Primary CMV Onset Primary CMV Onseta Relapsing Viremia
23 50 M Idiopathic Pulmonary Fibrosis CSA 175/100, RAPA 11,Pred 51 108 -
24 31 F Cystic Fibrosis TAC 1.52, MMF 0.52,Pred 101 96 +
25 34 F Primary Pulmonary Hypertension TAC 42, MMF 0.52,Pred 101 129 -
28 33 F Cystic Fibrosis TAC 62, MMF 0.52,Pred 101 210 -
29 62 F COPD TAC 2.52, MMF 0.52,Pred 101 168 +
31 55 M Cystic Fibrosis TAC 32, AZA 501,Pred 51 248 -
33 51 F Idiopathic Pulmonary Fibrosis TAC 22, MMF 0.53,Pred 7.51 186 +
34 59 F COPD TAC 42, MMF 0.252,Pred 101 174 -
35 27 M Cystic Fibrosis TAC 12, MMF 0.52,Pred 7.51 219 -
36 49 F Idiopathic Pulmonary Fibrosis TAC 42, MMF 0.252,Pred 101 167 +
37 56 F Obliterative Bronchiolitis TAC 52, MMF 0.54,Pred 101 133 -
38 56 M COPD TAC 12, MMF 12,Pred 101 155 -
40 54 F COPD TAC 1.52, MMF 0.54,Pred 151 122 -
41 64 F Bronchiectasis TAC 42, MMF 0.52,Pred 51 184 -
43 51 M Sarcoidosis TAC 42, MMF 0.52,Pred 151 83 +
45 21 M Cystic Fibrosis TAC 2.52, MMF 0.53,Pred 151 92 -
46 59 M COPD TAC 1.52, MMF 12,Pred 201 37 +
48 47 M Idiopathic Pulmonary Fibrosis TAC 22, MMF 0.252,Pred 101 162 +
51 41 F Pulmonary Hypertension TAC 22, MMF 0.52,Pred 7.51 214 -
53 35 F Cystic Fibrosis TAC 22, MMF 0.52,Pred 101 125 +
56 61 F COPD TAC 12, MMF 0.52,Pred 101 142 +
57 56 M Idiopathic Pulmonary Fibrosis TAC 22, MMF 0.252,Pred 101 118 +
60 62 M Idiopathic Pulmonary Fibrosis TAC 42, MMF 0.252,Pred 101 410 -
Summaryc 48.4(12.5) M 43.4 % 160.1 (73.7) + 43.4 %
a

Days post-transplant

b

Viral load at time of sampling

c

Values represent mean or percent of indicated group (SD)

AZA, azathioprine (dose in milligrams); COPD, chronic obstructive pulmonary disease; CSA, cyclosporine (dose in milligrams); F, female; M, male; MMF, mycophenolate mofetil (dose in grams); Pred, prednisone (dose in milligrams); TAC, tacrolimus (dose in milligrams with superscript times per day).